Could nanoparticle corona characterization help for biological consequence prediction?

Could nanoparticle corona characterization help for biological consequence prediction?

As soon as they enter a biological medium (cell culture medium for in vitro, blood or plasma for in vivo studies), nanoparticles, in most cases, see their surface covered by biomolecules, especially proteins. What the cells see is thus not the ideal nanoparticle concocted by chemists, meaning the biomolecular corona could have great biological and physiological repercussions, sometimes masking ...

Facile Magnesium Doped Zinc Oxide ‎Nanoparticle Fabrication and ‎Characterization for Biological Benefits

   Zinc oxide (ZnO) is the most common and widely utilized nanomaterial for biological applications due to their unique characteristics, such as biocompatibility, biosafety and antimicrobial along with thermal stability and mechanical strength. Magnesium (Cu) is considered as a significant dopant for ZnO due to their almost similar ionic radii and their role in biological activitie...

Nanoparticle size and surface properties determine the protein corona with possible implications for biological impacts.

Nanoparticles in a biological fluid (plasma, or otherwise) associate with a range of biopolymers, especially proteins, organized into the "protein corona" that is associated with the nanoparticle and continuously exchanging with the proteins in the environment. Methodologies to determine the corona and to understand its dependence on nanomaterial properties are likely to become important in bio...

Could interferon help treat Ebola?

G-Quadruplexes: Prediction, Characterization, and Biological Application.

Guanine (G)-rich sequences in nucleic acids can assemble into G-quadruplex structures that involve G-quartets linked by loop nucleotides. The structural and topological diversity of G-quadruplexes have attracted great attention for decades. Recent methodological advances have advanced the identification and characterization of G-quadruplexes in vivo as well as in vitro, and at a much higher res...